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middle-aged man

Practice targeted AMC-style multiple-choice questions on middle-aged man.

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A 45-year-old man presents to the emergency department with severe epigastric pain radiating to the back. He has a history of alcohol use disorder and has been drinking heavily over the past week. On examination, he is febrile, tachycardic, and has abdominal tenderness. Laboratory tests reveal elevated serum lipase and amylase levels. What is the most appropriate initial management for this patient?

A. Oral antibiotics
B. Intravenous fluid resuscitation
C. Nasogastric tube insertion
D. Endoscopic retrograde cholangiopancreatography (ERCP)
E. Immediate surgical consultation
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 62-year-old male presents with a three-month history of intermittent rectal bleeding and altered bowel habits. His past medical history is unremarkable. A colonoscopy was performed, and a still image is shown. What is the MOST appropriate next step in management?

A. Recommend a high-fiber diet and monitor symptoms
B. Administer high-dose corticosteroids
C. Prescribe a course of broad-spectrum antibiotics
D. Surgical resection
E. Initiate iron supplementation and repeat colonoscopy in 6 months
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A 45-year-old man presents with chronic cough, weight loss, and night sweats. Chest X-ray shows apical infiltrates. Sputum smear for AFB is negative. What is the most appropriate next step in management?

A. Perform a bronchoscopy with lavage.
B. Order a CT scan of the chest.
C. Start empirical anti-tuberculosis treatment.
D. Discharge with symptomatic treatment and review.
E. Repeat sputum smear and culture, including nucleic acid amplification test (NAAT).
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 45-year-old man presents with a bulge in his right groin that he noticed a few weeks ago. It's more prominent when he coughs or strains. Examination reveals the finding in the image. He denies pain. What is the MOST likely diagnosis?

A. Hydrocele
B. Lipoma
C. Indirect inguinal hernia
D. Direct inguinal hernia
E. Femoral hernia
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with a low-grade fever (38.1°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His vital signs are stable: BP 130/80 mmHg, HR 78 bpm, RR 16/min, SpO2 98% on air. Blood tests show a white cell count of 12.5 x 10^9/L and CRP 45 mg/L. An abdominal CT scan is performed (image provided). Following successful management of this acute episode, what is the most appropriate next step regarding long-term assessment of the colon?

A. Repeat CT scan in 3 months to assess resolution.
B. Refer for surgical consultation for elective colectomy.
C. Schedule a colonoscopy within 6-8 weeks.
D. Perform a barium enema to assess the extent of diverticular disease.
E. Advise a high-fibre diet and no further investigation unless symptoms recur.
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 38-year-old man presents with sudden onset severe left flank pain radiating to the groin, associated with nausea. He is afebrile, blood pressure 140/90 mmHg, heart rate 95 bpm. Urinalysis shows microscopic haematuria. Serum creatinine is 80 µmol/L. An ultrasound is performed. Considering the clinical presentation and the findings demonstrated in the provided image, which of the following best explains the mechanism of the patient's pain?

A. Spasm of the renal artery
B. Increased pressure within the renal pelvis and collecting system
C. Ischaemia of the renal medulla
D. Distension of the renal capsule due to oedema
E. Inflammation of the renal parenchyma
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 35-year-old man presents with a painless lesion on his nose, present for 6 months. Examination reveals the image shown. What is the MOST likely diagnosis?

A. Angioma
B. Squamous cell carcinoma
C. Melanoma
D. Basal cell carcinoma
E. Eosinophilic granuloma
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with a low-grade fever (38.1°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His vital signs are stable: BP 130/80 mmHg, HR 78 bpm, RR 16/min, SpO2 98% on air. Blood tests show a white cell count of 12.5 x 10^9/L and CRP 45 mg/L. An abdominal CT scan is performed (image provided). Based on the clinical presentation and the provided image, what is the most appropriate setting for this patient's initial management?

A. Inpatient admission for intravenous antibiotics and observation.
B. Outpatient management with oral antibiotics and analgesia.
C. Admission for bowel rest and total parenteral nutrition.
D. Urgent surgical consultation for potential intervention.
E. Discharge home with only analgesia and dietary advice.
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 62-year-old male presents to his general practitioner complaining of a dragging sensation in his right groin, particularly noticeable when standing for prolonged periods or straining during bowel movements. He denies any acute pain, nausea, vomiting, or changes in bowel habits. His past medical history is significant for benign prostatic hyperplasia (BPH) managed with tamsulosin. On examination, the patient is afebrile with normal vital signs. Palpation of the abdomen is unremarkable. Examination of the groin reveals the finding shown in the image. The swelling increases with coughing. Which of the following is the MOST appropriate next step in the management of this patient?

A. Urgent referral to the emergency department for suspected strangulation
B. Initiation of high-dose analgesics and close observation
C. Referral to a physiotherapist for core strengthening exercises
D. Prescription of a scrotal support and reassurance
E. Referral to a general surgeon for elective repair
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A 50-year-old Aboriginal man presents for a routine check. He has a history of smoking and lives in a remote community. What screening is most important to address his increased risk?

A. Cardiovascular risk assessment and diabetes screening
B. Glaucoma screening
C. Prostate cancer screening
D. Vitamin D deficiency screening
E. Osteoporosis screening
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old male with a history of mild dysphagia and iron deficiency anemia presents for further evaluation. He denies any recent weight loss or hematemesis. An abdominal CT scan with contrast is performed, the axial view is shown. What is the MOST likely underlying cause of his anemia?

A. Angiodysplasia
B. Cameron lesions
C. Gastric malignancy
D. Duodenal ulcer
E. Esophageal varices
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 58-year-old male presents with iron deficiency anemia and a change in bowel habits. A colonoscopy was performed, and the image is shown. Biopsies were taken. Assuming the biopsies confirm malignancy, what is the next step?

A. Repeat colonoscopy in 6 months
B. Referral to a gastroenterologist for endoscopic mucosal resection
C. Fecal immunochemical test (FIT)
D. Initiate chemotherapy
E. CT scan of the abdomen and pelvis
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 55-year-old male presents to his GP complaining of bilateral breast tenderness and swelling over the past six months. He denies nipple discharge, weight changes, or other systemic symptoms. His past medical history is unremarkable, and he takes no regular medications. Physical examination reveals the findings shown in the image. His vital signs are within normal limits. Considering the most likely underlying cause suggested by the clinical presentation and image, which of the following is the most appropriate initial investigation?

A. Fine needle aspiration of the breast tissue
B. Chest X-ray
C. Mammography
D. Liver function tests and renal function tests
E. Serum testosterone, LH, FSH, estradiol, and prolactin levels
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 45-year-old male presents with intermittent abdominal pain and melena. The provided image was obtained. What is the most appropriate next step in management?

A. Surgical resection of affected bowel segments
B. Perform colonoscopy to rule out other causes of bleeding
C. Initiate a trial of high-dose corticosteroids
D. Prescribe iron supplementation and monitor hemoglobin levels
E. Start empiric antibiotic therapy for suspected bacterial overgrowth
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 48-year-old man presents with a 2-year history of progressive, tender breast enlargement causing significant distress. Initial investigations including liver function tests, renal function tests, and basic hormonal assays (LH, FSH, testosterone, oestradiol) were largely within normal limits, except for a mildly elevated oestradiol. He takes no regular medications and denies recreational drug use. He is otherwise well and his physical examination is unremarkable apart from the findings shown in the image. Considering the clinical presentation and the findings, what is the most appropriate next step in his management?

A. Order a CT scan of the abdomen and pelvis to exclude occult malignancy.
B. Initiate a trial of tamoxifen for 3-6 months.
C. Reassure the patient that this is benign and requires no further intervention.
D. Referral to a plastic or general surgeon for consideration of reduction mammoplasty.
E. Repeat hormonal assays including prolactin and hCG.
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A 45-year-old man presents to the emergency department with sudden onset of severe chest pain radiating to his back. He describes the pain as tearing in nature. He has a history of hypertension and is a smoker. On examination, his blood pressure is 180/110 mmHg in the right arm and 160/100 mmHg in the left arm. His heart rate is 110 bpm, and he has diminished pulses in the left radial artery. A chest X-ray shows a widened mediastinum. Which of the following is the most appropriate next step in management?

A. Immediate surgical consultation
B. CT angiography of the chest
C. Nitroglycerin infusion
D. Intravenous beta-blockers
E. Echocardiography
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 58-year-old male presents to the emergency department complaining of right groin pain that started approximately 6 hours ago. He reports noticing a bulge in his groin for several months, which he could usually push back in. However, today he is unable to reduce it, and the pain has become progressively severe. He denies any fever, nausea, or vomiting. His past medical history includes hypertension and hyperlipidemia, both well-controlled with medications. On examination, his vital signs are stable: blood pressure 130/80 mmHg, heart rate 80 bpm, respiratory rate 16 bpm, and temperature 37.0°C. Abdominal examination is benign. Examination of the groin reveals the finding shown in the image. The area is tender to palpation. Which of the following is the MOST appropriate next step in the management of this patient?

A. Surgical consultation for emergent repair
B. Ultrasound of the groin to rule out testicular torsion
C. Prescription for a truss and referral to a general surgeon for elective repair
D. CT scan of the abdomen and pelvis with intravenous contrast
E. Trial of manual reduction with sedation and analgesia
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old male presents with postprandial vomiting and persistent retrosternal discomfort. He reports feeling full quickly after eating only small amounts. An abdominal CT scan is performed, the axial view is shown. What is the MOST likely underlying mechanism contributing to this patient's symptoms?

A. Gastric malignancy
B. Pyloric stenosis
C. Esophageal dysmotility
D. Mechanical obstruction of the gastric outflow
E. Increased gastric acid production
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 55-year-old man presents with the condition depicted, which has been present for 12 months and is mildly tender. Initial investigations including hormonal profile, liver function tests, and renal function tests are unremarkable. He takes no regular medications. Considering the clinical presentation and the findings shown, what is the most appropriate next step in the management of this patient?

A. Referral for surgical reduction mammoplasty.
B. Prescription of tamoxifen for symptom relief.
C. Further investigation for rare endocrine causes (e.g., hCG-producing tumour).
D. Urgent referral for breast imaging (ultrasound/mammography).
E. Reassurance and observation with review as needed.
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old male presents with concerns about breast enlargement over the past year. He denies pain or nipple discharge. He takes no medications and has no known medical conditions. Examination reveals the findings in the image. What is the MOST appropriate initial investigation?

A. Reassurance and observation
B. Mammogram
C. Liver function tests
D. Prolactin level
E. Serum testosterone and estradiol levels
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A 55-year-old man with prostate cancer and bony metastases is experiencing severe pain and is not responding to strong analgesia. He is reluctant to use NSAIDs. What is the next step?

A. Fentanyl patch
B. Buprenorphine patch
C. Oral oxycodone CR.
D. Oral IR morphine.
E. SC morphine.
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 32-year-old male with a history of Crohn's disease presents with worsening abdominal pain, diarrhea, and a low-grade fever. He reports that his symptoms have been progressively worsening over the past few weeks despite being compliant with his prescribed mesalamine. A CT scan of the abdomen and pelvis is performed, as shown. What is the MOST appropriate next step in management?

A. Schedule a colonoscopy with biopsy
B. Start a course of oral prednisone
C. Initiate infliximab therapy
D. Increase the dose of mesalamine
E. Prescribe a course of oral ciprofloxacin and metronidazole
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old male presents with concerns about breast enlargement over the past year. He denies pain or nipple discharge. He takes no medications and reports no significant past medical history. Examination reveals the findings in the image. What is the MOST appropriate initial investigation?

A. Liver function tests
B. Prolactin level
C. Mammography
D. Serum testosterone and estradiol levels
E. Fine needle aspiration
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 62-year-old male with LLQ pain and mild fever has the CT abdomen shown. What is the MOST appropriate next step in management?

A. Colonoscopy to rule out malignancy
B. Oral antibiotics and outpatient follow-up
C. Stool culture to rule out infectious colitis
D. IV antibiotics and admission for observation
E. Surgical consultation for possible resection
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A 45-year-old man with a history of hypertension presents to the emergency department with palpitations and lightheadedness. His ECG shows a regular narrow-complex tachycardia at a rate of 180 bpm. There are no visible P waves, and the QRS duration is 0.08 seconds. He is hemodynamically stable. Which of the following is the most appropriate initial management?

A. Synchronized cardioversion
B. Observation without intervention
C. Intravenous adenosine
D. Vagal maneuvers
E. Intravenous metoprolol
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old man presents with concerns about breast enlargement over the past year. He denies pain or nipple discharge. He takes medication for hypertension. Examination reveals the findings in the image. Which of the following is the MOST appropriate initial investigation?

A. Review medication list and consider alternative antihypertensive
B. Reassurance and observation
C. Fine needle aspiration of breast tissue
D. Serum prolactin and testosterone levels
E. Mammogram and ultrasound of the breasts
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 60-year-old man presents with a reducible right groin bulge, as seen in the image. He reports mild discomfort. What is the most appropriate initial management?

A. Surgical referral for elective repair
B. CT scan of the abdomen and pelvis
C. Prescription of a truss support
D. Reassurance and watchful waiting
E. Strong analgesia and urgent surgical review
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 55-year-old man presents to his GP complaining of a long-standing, intermittent swelling in his right groin that becomes more noticeable when he coughs or lifts heavy objects. It is usually painless and he can push it back in. His vital signs are normal. Considering the clinical presentation and the appearance shown, what is the most appropriate initial management?

A. Urgent surgical exploration
B. Watchful waiting with regular review
C. Elective surgical repair
D. Order an ultrasound scan of the groin
E. Prescribe a truss for support
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 32-year-old male with Crohn's disease presents with worsening abdominal pain and diarrhea despite being on maintenance infliximab. He denies fever or blood in his stool. An abdominal CT and MRI are performed. Based on the imaging, what is the MOST appropriate next step in management?

A. Initiate treatment with ustekinumab
B. Perform a colonoscopy with biopsy
C. Prescribe a course of oral metronidazole
D. Start a course of oral budesonide
E. Increase the dose of infliximab
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 50-year-old man presents with a slowly growing, asymptomatic nasal lesion. He reports no trauma or fever. Examination reveals the image shown. What is the MOST likely long-term outcome if left untreated?

A. Transformation to squamous cell carcinoma
B. Local tissue destruction
C. Metastatic spread
D. Spontaneous resolution
E. Development of systemic lupus erythematosus
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 55-year-old man presents to his GP with a lesion on his nose that has been slowly enlarging over the past 4 months. He reports no associated pain, itching, or bleeding. He is otherwise well, with no significant past medical history. On examination, vital signs are within normal limits. The lesion is as shown in the image. Considering the clinical presentation and the appearance of the lesion, what is the most appropriate initial step in the management of this patient?

A. Refer the patient directly for Mohs micrographic surgery.
B. Arrange for cryotherapy to the lesion.
C. Prescribe a course of oral antibiotics.
D. Excisional or incisional biopsy of the lesion.
E. Prescribe a high-potency topical corticosteroid cream.
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A 45-year-old man presents to the clinic with a 3-month history of persistent cough and shortness of breath. He is a non-smoker and works as a carpenter. On examination, there are bilateral inspiratory crackles at the lung bases. A chest X-ray shows reticular opacities predominantly in the lower lobes. Pulmonary function tests reveal a restrictive pattern. What is the most likely diagnosis?

A. Bronchiectasis
B. Asthma
C. Idiopathic pulmonary fibrosis
D. Chronic obstructive pulmonary disease
E. Sarcoidosis
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with a low-grade fever (38.1°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His vital signs are stable: BP 130/80 mmHg, HR 78 bpm, RR 16/min, SpO2 98% on air. Blood tests show a white cell count of 12.5 x 10^9/L and CRP 45 mg/L. An abdominal CT scan is performed (image provided). Considering the clinical context and the findings demonstrated in the provided image, what is the most appropriate recommendation regarding subsequent investigation of the colon following resolution of the acute symptoms?

A. Barium enema within 3 months.
B. Flexible sigmoidoscopy within 1 week.
C. Urgent colonoscopy within 24 hours.
D. No further colonic investigation is necessary.
E. Colonoscopy within 6-8 weeks.
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A 55-year-old man with a history of hypertension and smoking presents for a routine check-up. He is concerned about his risk of cardiovascular disease and asks for advice on lifestyle modifications. Which of the following lifestyle changes would most significantly reduce his risk of cardiovascular events?

A. Adopting a Mediterranean diet
B. Smoking cessation
C. Increasing physical activity
D. Limiting alcohol consumption
E. Reducing dietary salt intake
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 62-year-old male presents with jaundice and RUQ pain. An ERCP is performed, and the image is obtained. Following successful stone extraction, what is the MOST appropriate next step in managing this patient?

A. Sphincteroplasty
B. Ursodeoxycholic acid
C. Observation with serial LFTs
D. Percutaneous cholecystostomy
E. Cholecystectomy
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 40-year-old male presents with acute, severe left flank pain. An ultrasound is performed. What is the MOST likely underlying cause of the finding on the image?

A. Polycystic kidney disease
B. Renal cell carcinoma
C. Acute pyelonephritis
D. Ureteral obstruction
E. Renal vein thrombosis
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A 62-year-old man presents to the emergency department with a history of palpitations and dizziness that started suddenly 2 hours ago. He has a history of hypertension and is on lisinopril. He denies chest pain, shortness of breath, or syncope. On examination, his blood pressure is 110/70 mmHg, heart rate is 150 bpm (irregular), respiratory rate is 18 breaths per minute, and temperature is 36.7°C. An ECG is performed, showing an irregularly irregular rhythm with no distinct P waves and a narrow QRS complex. Which of the following is the most appropriate initial management step?

A. Initiation of anticoagulation therapy
B. Rate control with a beta-blocker
C. Immediate electrical cardioversion
D. Administration of adenosine
E. Rate control with digoxin
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 45-year-old male presents to the ED with left flank pain radiating to his groin. He reports nausea but no vomiting. Vitals are stable. A focused assessment with sonography for trauma (FAST) exam is performed, with a view obtained as shown. What is the MOST appropriate next step in management?

A. Perform a cystoscopy
B. Discharge with analgesics and follow-up with urology
C. Non-contrast CT of the abdomen and pelvis
D. Order serum lipase and amylase
E. Administer intravenous antibiotics
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A 55-year-old man presents to the emergency department with crushing chest pain radiating to his left arm and jaw. He is diaphoretic and appears anxious. An ECG shows ST-segment elevation in leads II, III, and aVF. What is the most appropriate immediate management?

A. Order a chest X-ray to rule out other causes
B. Start intravenous beta-blockers
C. Administer sublingual nitroglycerin
D. Provide oxygen therapy
E. Administer aspirin and initiate reperfusion therapy
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A 58-year-old man presents to the emergency department with severe epigastric pain radiating to the back, which started suddenly 6 hours ago. He has a history of alcohol use disorder and has been consuming large amounts of alcohol daily for the past 10 years. On examination, he is diaphoretic and in distress, with a blood pressure of 100/60 mmHg, heart rate of 120 bpm, and respiratory rate of 22 breaths per minute. Abdominal examination reveals tenderness in the epigastric region with guarding. Laboratory tests show elevated serum amylase and lipase levels. Which of the following is the most appropriate initial management step?

A. Intravenous fluid resuscitation
B. Immediate surgical consultation
C. Administration of proton pump inhibitors
D. Initiation of broad-spectrum antibiotics
E. Nasogastric tube insertion
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with subjective fever and chills. He denies nausea, vomiting, or change in bowel habits. On examination, he is afebrile, heart rate 85 bpm, blood pressure 130/80 mmHg. Abdominal examination reveals tenderness in the left iliac fossa without guarding or rebound. White cell count is 14 x 10^9/L, CRP 80 mg/L. A CT scan of the abdomen and pelvis is performed, the relevant axial image is shown. Considering the patient's presentation and the findings on the provided image, which of the following represents the most appropriate initial management strategy?

A. Discharge with only analgesia and advice to return if symptoms worsen
B. Urgent colonoscopy to assess the affected segment
C. Urgent surgical consultation for potential colectomy
D. Immediate inpatient admission for intravenous antibiotics
E. Outpatient management with oral antibiotics and analgesia
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old male presents with bilateral breast enlargement for 6 months. He denies pain, discharge, or skin changes. He reports taking saw palmetto for BPH. Examination reveals the findings in the image. What is the MOST likely cause?

A. Hyperthyroidism
B. Testicular cancer
C. Cirrhosis
D. Idiopathic
E. Medication side effect
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A 60-year-old Aboriginal man presents for a routine check-up. He has a history of smoking and lives in a remote community. Which screening is MOST important, considering higher prevalence in this population?

A. PSA
B. Mammography
C. Albuminuria
D. Colonoscopy
E. Thyroid function tests
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 45-year-old man presents to his GP with a lesion on his nose that he first noticed about 6 months ago. It has slowly increased in size but is not painful or itchy. He has no significant past medical history and takes no regular medications. On examination, vital signs are stable. The image shows the appearance of the lesion. Considering the clinical presentation and the appearance of the lesion shown, what is the most appropriate initial management step?

A. Reassure the patient and review in 3 months.
B. Excisional biopsy for histological assessment.
C. Prescribe a course of topical corticosteroid cream.
D. Refer immediately for Mohs micrographic surgery.
E. Arrange for cryotherapy in the clinic.
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A 58-year-old farmer presents with a 10-day history of fever, severe retro-orbital headache, myalgia, and profound fatigue. He denies cough or sore throat. Examination reveals mild scleral icterus. Liver function tests show elevated transaminases. He works closely with sheep and cattle. What is the most likely diagnosis?

A. Influenza
B. Leptospirosis
C. Brucellosis
D. Viral hepatitis A
E. Q fever
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Figure 3 of paper: Alveolar echinococcosis in a patient with immunosuppression.

(a) Abdominal gray-scale US shows an abscess-like hepatic image.
(b) Axial unenhanced CT shows a typical aspect of pyogenic liver abscess.
Image by Wenya Liu, Éric Delabrousse, Oleg Blagosklonov, Jing Wang, Hongchun Zeng, Yi Jiang, Jian Wang, Yongde Qin, Dominique Angèle Vuitton, Hao Wen CC BY 4.0 · Source

A 62-year-old male with a history of poorly controlled diabetes presents with fever, RUQ pain, and recent travel to a rural area. Lab results show elevated ALP and GGT. Imaging is performed. What is the MOST appropriate next step in management?

A. Metronidazole
B. Observation and serial imaging
C. Percutaneous drainage and antibiotics
D. Albendazole and surgical resection
E. Ceftriaxone and doxycycline
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with fever (38.2°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His blood pressure is 130/80 mmHg, heart rate 85 bpm, respiratory rate 16 bpm. Blood tests show a white cell count of 14 x 10^9/L and CRP 80 mg/L. A CT scan of the abdomen and pelvis is performed (image provided). Considering the patient's presentation and the findings on the provided image, which of the following is the most appropriate initial management strategy?

A. Intravenous antibiotics and hospital admission
B. Urgent surgical consultation for sigmoid colectomy
C. Oral antibiotics and outpatient management
D. Repeat CT scan in 24 hours to assess for progression
E. Immediate colonoscopy to assess the extent of disease
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old man presents with increasing postprandial fullness and epigastric discomfort. A CT scan of the abdomen is performed. Based on the image, what is the MOST appropriate next step in management?

A. Initiate a trial of high-dose proton pump inhibitors
B. Esophageal manometry to assess esophageal motility
C. Surgical consultation for consideration of fundoplication
D. Reassurance and dietary modification
E. Barium swallow study to evaluate for esophageal strictures
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 55-year-old man presents with the condition shown. He reports taking spironolactone for hypertension. What is the MOST appropriate next step?

A. Refer to endocrinology for hormonal evaluation
B. Initiate treatment with tamoxifen
C. Order a mammogram to rule out malignancy
D. Review and potentially adjust his antihypertensive medication
E. Reassure the patient that this is a normal age-related change
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old male presents to his GP complaining of bilateral breast enlargement over the past year. He denies any pain or tenderness. He takes no medications and reports no significant past medical history. Examination reveals the findings in the image. What is the MOST appropriate initial investigation?

A. Prolactin level
B. Liver function tests
C. Fine needle aspiration
D. Serum testosterone and estradiol levels
E. Mammography
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