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middle-aged man

Practice targeted AMC-style multiple-choice questions on middle-aged man.

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A 59-year-old with recurrent gout, on multiple medications, has started allopurinol and naproxen. The uric acid level is 0.58. What is the target uric acid level?

A. Less than 0.40 mmol/L
B. Less than 0.30 mmol/L
C. Less than 0.36 mmol/L
D. Less than 0.20 mmol/L
E. Less than 0.50 mmol/L
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 45-year-old male presents with intermittent abdominal pain and melena. The provided image was obtained. What is the most likely underlying cause?

A. Henoch-Schönlein purpura
B. Cystic fibrosis
C. Meckel's diverticulum
D. Peutz-Jeghers syndrome
E. Blue rubber bleb nevus syndrome
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 55-year-old man presents to his general practitioner with a six-month history of bilateral breast tenderness and swelling. He is otherwise asymptomatic, reporting no nipple discharge, skin changes, or palpable lumps. His medical history includes well-controlled hypertension on amlodipine. He denies illicit drug use or significant alcohol intake. On examination, the finding shown in the image is noted. Given this presentation, what is the most appropriate initial diagnostic step?

A. Advise lifestyle modification and review in three months.
B. Serum hormonal profile including testosterone, oestradiol, LH, FSH, prolactin, and hCG.
C. Referral for surgical consultation and potential biopsy.
D. Bilateral diagnostic mammography to rule out malignancy.
E. Ultrasound examination of the breast and axillary lymph nodes.
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A 62-year-old male presents to his general practitioner with a six-month history of a painless bulge in his right groin. On examination, a soft swelling is palpable in the right inguinal region, which increases in size on coughing or straining. The swelling is located medial to the inferior epigastric vessels. Which of the following is the most appropriate initial management strategy according to current Australian guidelines?

A. Reassurance and watchful waiting, with advice to return if symptoms worsen.
B. Urgent referral to an emergency department for exclusion of strangulation.
C. Prescription of a truss to provide symptomatic relief.
D. Referral to a physiotherapist for core strengthening exercises.
E. Referral to a general surgeon for consideration of elective repair.
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A 58-year-old man presents to the emergency department with chest pain radiating to his left arm. His ECG shows ST-segment elevation in leads II, III, and aVF. What is the most appropriate immediate management?

A. Administer thrombolytic therapy
B. Perform an echocardiogram to assess cardiac function
C. Administer sublingual nitroglycerin and observe
D. Start intravenous heparin and admit to the coronary care unit
E. Administer aspirin and initiate primary percutaneous coronary intervention (PCI)
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 45-year-old male with Crohn's presents with persistent right lower quadrant pain. Stool studies are negative. Review the imaging. What is the MOST likely complication?

A. Toxic megacolon
B. Fistula formation
C. Appendicitis
D. Small bowel obstruction
E. Perforation
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A 60-year-old man with a Popeye deformity has no pain but reports mild weakness in supination. What is the most appropriate management?

A. Surgical repair
B. NSAIDs
C. Corticosteroid injection
D. Observation
E. Physical therapy
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 35-year-old male presents with a painless lesion on his nose that has been present for several months. He denies any trauma or recent illness. Examination reveals the image shown. What is the most appropriate initial management?

A. Topical corticosteroids
B. Topical retinoids
C. Excisional biopsy
D. Oral antibiotics
E. Cryotherapy
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 55-year-old male presents to his GP complaining of bilateral breast tenderness and swelling over the past 6 months. He denies nipple discharge, weight changes, or other systemic symptoms. His vital signs are normal. He takes no regular medications. Considering the clinical presentation and the provided image, which of the following investigations is the most appropriate initial step in evaluating this patient?

A. Chest X-ray
B. Bilateral mammography
C. Fine needle aspiration biopsy
D. Serum testosterone, oestradiol, LH, and FSH
E. Liver function tests and renal function tests
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 45-year-old male presents to the emergency department with sudden onset severe left flank pain radiating to the groin. He reports some nausea but no vomiting. His temperature is 37.5°C, pulse 88 bpm, BP 130/80 mmHg, respiratory rate 16/min, oxygen saturation 98% on room air. On examination, he has significant left costovertebral angle tenderness. Urinalysis shows microscopic haematuria and trace leukocytes. His creatinine is 90 µmol/L (baseline unknown). An ultrasound of the kidneys is performed, shown in the image. Based on the clinical presentation and the finding shown in the image, which of the following developments would most strongly necessitate urgent urological intervention?

A. Discovery of bilateral hydronephrosis on repeat imaging.
B. Passage of a small stone fragment.
C. Persistence of severe pain despite adequate analgesia.
D. Development of fever and rigors.
E. Increase in serum creatinine to 150 µmol/L.
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 52-year-old man presents with right groin discomfort, worse with standing. Examination reveals the finding in the image. What is the MOST appropriate next step?

A. CT abdomen and pelvis
B. Reassurance and watchful waiting
C. Surgical referral for elective repair
D. Urgent surgical referral
E. Prescription of a truss
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with a low-grade fever (38.1°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His vital signs are stable: BP 130/80 mmHg, HR 78 bpm, RR 16/min, SpO2 98% on air. Blood tests show a white cell count of 12.5 x 10^9/L and CRP 45 mg/L. An abdominal CT scan is performed (image provided). Based on the clinical presentation and the provided image, what is the most appropriate setting for this patient's initial management?

A. Inpatient admission for intravenous antibiotics and observation.
B. Outpatient management with oral antibiotics and analgesia.
C. Admission for bowel rest and total parenteral nutrition.
D. Urgent surgical consultation for potential intervention.
E. Discharge home with only analgesia and dietary advice.
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Synchronous multiple small bowel intussusceptions in an adult with blue rubber bleb naevus syndrome. CT scan of abdomen showing i) multiple intussusceptions demonstrating doughnut signs (white arrows), intussusceptiens [A], intussusceptum [B], distended loop of small

bowel [C] and ii) haemangioma of right quadratus lumborum muscle (dark arrow).
Image by Lee C, Debnath D, Whitburn T, Farrugia M, Gonzalez F CC BY 2.0 · Source

A 45-year-old male with a known history of Blue Rubber Bleb Naevus Syndrome, characterised by recurrent gastrointestinal bleeding and multiple cutaneous vascular lesions, presents to the emergency department with acute onset severe, colicky abdominal pain, nausea, and vomiting. On examination, his abdomen is distended and diffusely tender with reduced bowel sounds. Vital signs are within normal limits. An urgent abdominal CT scan is performed. Considering the patient's history, acute presentation, and the findings on the abdominal CT scan, what is the most appropriate immediate management strategy?

A. Urgent surgical consultation for operative management
B. Attempt non-operative reduction via hydrostatic or pneumatic enema
C. Perform urgent upper and lower endoscopy to identify bleeding lesions
D. Initiate conservative management with intravenous fluids and nasogastric tube insertion
E. Administer broad-spectrum antibiotics and observe closely
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 55-year-old man presents with a slowly growing lesion on his nose that he first noticed about 6 months ago. He reports occasional mild discomfort but no bleeding. He has a history of significant sun exposure due to his occupation. His medical history is otherwise unremarkable. On examination, vital signs are normal. The lesion appears as shown in the image. Regional lymph nodes are not enlarged. Considering the patient's history, risk factors, and the appearance of the lesion, what is the most appropriate initial step in the management of this patient?

A. Apply a high-potency topical corticosteroid cream
B. Excisional or incisional biopsy of the lesion
C. Observe the lesion for a further 3 months and review
D. Order a CT scan of the facial bones and sinuses
E. Refer directly to a plastic surgeon for cosmetic removal
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A 60-year-old man presents to the emergency department with sudden onset of chest pain and shortness of breath. He has a history of chronic obstructive pulmonary disease (COPD) and is a current smoker. On examination, he is tachypneic and has decreased breath sounds on the right side. A chest X-ray reveals a large right-sided pneumothorax. What is the most appropriate initial management?

A. Start intravenous antibiotics
B. Insert a chest tube
C. Perform needle decompression
D. Administer high-flow oxygen
E. Order a CT scan of the chest
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 58-year-old male presents with iron deficiency anemia and a change in bowel habits. A colonoscopy was performed, and the image is shown. Biopsies were taken. Assuming the biopsies confirm malignancy, what is the next step?

A. Repeat colonoscopy in 6 months
B. Referral to a gastroenterologist for endoscopic mucosal resection
C. Fecal immunochemical test (FIT)
D. Initiate chemotherapy
E. CT scan of the abdomen and pelvis
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Fluoroscopic image of common bile duct stone seen at the time of ERCP. The stone is impacted in the distal common bile duct.
Image by Samir धर्म at en.wikipedia CC BY-SA 3.0 · Source

A 62-year-old male presents with jaundice and right upper quadrant pain. Initial labs show elevated bilirubin and alkaline phosphatase. An ERCP is performed, and the image is obtained. What is the MOST appropriate next step in management?

A. Percutaneous transhepatic biliary drainage
B. Cholecystectomy
C. Sphincterotomy and stone extraction
D. Observation with serial liver function tests
E. Ursodeoxycholic acid administration
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 45-year-old male presents to the emergency department with sudden onset severe left flank pain radiating to the groin. He reports some nausea but no vomiting. His temperature is 37.5°C, pulse 88 bpm, BP 130/80 mmHg, respiratory rate 16/min, oxygen saturation 98% on room air. On examination, he has significant left costovertebral angle tenderness. Urinalysis shows microscopic haematuria and trace leukocytes. His creatinine is 90 µmol/L (baseline unknown). An ultrasound of the kidneys is performed, shown in the image. Based on the clinical presentation and the finding shown in the image, what is the most appropriate immediate next step in management?

A. Admit for observation, serial renal function tests, and pain management.
B. Arrange urgent non-contrast CT scan of the kidneys, ureters, and bladder.
C. Arrange urgent flexible cystoscopy and retrograde pyelography.
D. Administer intravenous fluids, opioid analgesia, and prescribe tamsulosin for medical expulsive therapy.
E. Urgent urology consultation for consideration of upper tract decompression.
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A 45-year-old man presents to the emergency department with sudden onset of severe chest pain radiating to his back. He describes the pain as tearing in nature. He has a history of hypertension and is a smoker. On examination, his blood pressure is 180/110 mmHg in the right arm and 160/100 mmHg in the left arm. His heart rate is 110 bpm, and he has diminished pulses in the left radial artery. A chest X-ray shows a widened mediastinum. Which of the following is the most appropriate next step in management?

A. Immediate surgical consultation
B. CT angiography of the chest
C. Nitroglycerin infusion
D. Intravenous beta-blockers
E. Echocardiography
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CT scan of hepatocellular carcinoma, without and with IV contrast
Image by Zhenyu Pan, Guozi Yang, Tingting Yuan, Lihua Dong, Lihua Dong CC BY 4.0 · Source

A 62-year-old male presents to the emergency department with right upper quadrant abdominal pain, weight loss, and jaundice. He has a known history of chronic hepatitis C infection. His vital signs are stable. Physical examination reveals hepatomegaly and mild ascites. The patient denies any alcohol consumption. Laboratory investigations reveal elevated alpha-fetoprotein (AFP) levels. A CT scan of the abdomen with and without contrast is performed, as shown. Based on the imaging and clinical findings, what is the MOST appropriate next step in management?

A. Referral to a hepatologist for consideration of liver transplantation
B. Percutaneous liver biopsy for histological confirmation
C. Observation with serial AFP measurements every 3 months
D. Administration of intravenous antibiotics for suspected cholangitis
E. Initiation of antiviral therapy for hepatitis C
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 45-year-old man presents to his GP with a lesion on his nose that has been present for several months and seems to be slowly enlarging. He denies pain, itching, or bleeding. He works outdoors but reports using sunscreen inconsistently. His past medical history is unremarkable, and he takes no regular medications. On examination, vital signs are stable. Regional lymph nodes are not palpable. The lesion is as shown in the image. Considering the clinical presentation, risk factors, and the appearance of the lesion, which of the following represents the most appropriate initial step in establishing a definitive diagnosis and guiding management?

A. Referral for cryotherapy
B. Application of topical corticosteroid cream twice daily
C. Punch biopsy for bacterial culture and sensitivity
D. Excisional or incisional biopsy for histological examination
E. Reassurance and review in three months
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 55-year-old man presents to his GP with a persistent lesion on his nose that has been present for several months and has not changed significantly in size or appearance. He reports it is occasionally itchy but otherwise asymptomatic. His medical history is unremarkable, and vital signs are within normal limits. On examination, you observe the lesion shown in the image. Considering the appearance of this lesion, what is the most appropriate initial step in the management of this patient?

A. Perform a punch or shave biopsy of the lesion.
B. Advise watchful waiting and review in 6 months if it changes.
C. Prescribe a 7-day course of oral flucloxacillin.
D. Initiate treatment with topical hydrocortisone 1%.
E. Refer for Mohs micrographic surgery.
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old male presents with concerns about breast enlargement over the past year. He denies pain or nipple discharge. He takes no medications and reports no significant past medical history. Examination reveals the findings in the image. What is the MOST appropriate initial investigation?

A. Liver function tests
B. Prolactin level
C. Mammography
D. Serum testosterone and estradiol levels
E. Fine needle aspiration
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 60-year-old man presents with a reducible right groin bulge, as seen in the image. He reports mild discomfort. What is the most appropriate initial management?

A. Surgical referral for elective repair
B. CT scan of the abdomen and pelvis
C. Prescription of a truss support
D. Reassurance and watchful waiting
E. Strong analgesia and urgent surgical review
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A 55-year-old man with a history of type 2 diabetes mellitus presents with polyuria, polydipsia, and fatigue. His blood tests reveal a fasting blood glucose level of 15 mmol/L and HbA1c of 9.5%. He is currently on metformin. What is the most appropriate next step in management?

A. Increase the dose of metformin
B. Switch to insulin therapy
C. Add a DPP-4 inhibitor
D. Add a sulfonylurea
E. Start lifestyle modifications
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old man presents with concerns about breast enlargement. Examination reveals the findings in the image. Which of the following is the MOST appropriate initial investigation?

A. Liver function tests
B. Medication review
C. Serum prolactin
D. Mammogram
E. Testicular ultrasound
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Ileitis terminalis bei langjaehrigem Morbus Crohn 63W - CT und MRT - 001
Image by Hellerhoff CC BY-SA 4.0 · Source

A 32-year-old male with Crohn's disease presents with worsening abdominal pain and diarrhea despite being on maintenance infliximab. He denies fever or blood in his stool. An abdominal CT and MRI are performed. Based on the imaging, what is the MOST appropriate next step in management?

A. Initiate treatment with ustekinumab
B. Perform a colonoscopy with biopsy
C. Prescribe a course of oral metronidazole
D. Start a course of oral budesonide
E. Increase the dose of infliximab
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 45-year-old man presents with the finding shown. He denies pain but is concerned about its appearance. What is the MOST appropriate initial step?

A. Surgical referral for elective repair
B. Referral for physiotherapy
C. Reassurance and observation
D. Prescription for a scrotal support
E. CT scan of the abdomen and pelvis
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A 40-year-old patient with schizophrenia is started on risperidone. His GP recommends regular monitoring. What parameters should be monitored?

A. Serum calcium
B. Thyroid function tests
C. Liver function tests
D. Vitamin D levels
E. Blood glucose and lipids
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A 55-year-old man with a history of hypertension and smoking presents for a routine check-up. He is concerned about his risk of cardiovascular disease and asks for advice on lifestyle modifications. Which of the following lifestyle changes would most significantly reduce his risk of cardiovascular events?

A. Adopting a Mediterranean diet
B. Smoking cessation
C. Increasing physical activity
D. Limiting alcohol consumption
E. Reducing dietary salt intake
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 40-year-old male presents with acute, severe left flank pain. An ultrasound is performed. What is the MOST likely underlying cause of the finding on the image?

A. Polycystic kidney disease
B. Renal cell carcinoma
C. Acute pyelonephritis
D. Ureteral obstruction
E. Renal vein thrombosis
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 58-year-old male presents with fatigue and iron deficiency anemia. Colonoscopy reveals the image shown. Biopsies are taken. Assuming pathology confirms malignancy, what is the MOST appropriate next investigation to determine disease stage?

A. CT scan of the abdomen and pelvis
B. PET-CT scan
C. Endoscopic ultrasound
D. MRI of the abdomen and pelvis
E. Carcinoembryonic antigen (CEA) level
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 45-year-old male presents with a painless lesion on his nose that has been present for several months. He denies any trauma or recent illness. Examination reveals the image shown. What is the MOST appropriate initial management?

A. Observation with serial photography
B. Topical antifungal cream
C. Topical corticosteroid application
D. Biopsy for histopathological examination
E. Cryotherapy
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A 55-year-old man with a history of hypertension and stable angina is prescribed a new medication. He reports experiencing a persistent dry cough since starting the medication. Which drug is most likely responsible for this side effect?

A. Amlodipine
B. Losartan
C. Enalapril
D. Hydrochlorothiazide
E. Atenolol
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 55-year-old male presents with LLQ pain, fever, and increased WBC. A CT scan is performed, as shown. He is hemodynamically stable. What is the MOST appropriate initial management?

A. IV antibiotics and bowel rest
B. High-fiber diet and increased fluid intake
C. Surgical resection
D. Flexible sigmoidoscopy
E. Oral antibiotics and outpatient follow-up
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 45-year-old male presents to the ED with left flank pain radiating to his groin. He reports nausea but no vomiting. Vitals are stable. A focused assessment with sonography for trauma (FAST) exam is performed, with a view obtained as shown. What is the MOST appropriate next step in management?

A. Perform a cystoscopy
B. Discharge with analgesics and follow-up with urology
C. Non-contrast CT of the abdomen and pelvis
D. Order serum lipase and amylase
E. Administer intravenous antibiotics
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A 55-year-old man with type 2 diabetes mellitus presents for a routine follow-up. His HbA1c is 9.0% despite being on metformin 1000 mg twice daily. He has a BMI of 32 kg/m² and no history of cardiovascular disease. What is the most appropriate next step in his management?

A. Add a DPP-4 inhibitor
B. Increase the dose of metformin
C. Add a GLP-1 receptor agonist
D. Start basal insulin therapy
E. Add a sulfonylurea
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old male presents with bilateral breast enlargement for 6 months. He denies pain, discharge, or skin changes. He reports taking saw palmetto for BPH. Examination reveals the findings in the image. What is the MOST likely cause?

A. Hyperthyroidism
B. Testicular cancer
C. Cirrhosis
D. Idiopathic
E. Medication side effect
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A 60-year-old man presents to his GP with a 3-month history of fatigue, weight loss, and night sweats. He has a history of smoking and hypertension. On examination, he has palpable lymphadenopathy in the cervical and axillary regions. Blood tests reveal anemia and elevated lactate dehydrogenase (LDH). What is the most appropriate next step in the investigation of this patient?

A. PET scan
B. Excisional lymph node biopsy
C. CT scan of the chest and abdomen
D. Fine needle aspiration of the lymph node
E. Bone marrow biopsy
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 45-year-old man presents to his GP with a lesion on his nose that he first noticed about 6 months ago. It has slowly increased in size but is not painful or itchy. He has no significant past medical history and takes no regular medications. On examination, vital signs are stable. The image shows the appearance of the lesion. Considering the clinical presentation and the appearance of the lesion shown, what is the most appropriate initial management step?

A. Reassure the patient and review in 3 months.
B. Excisional biopsy for histological assessment.
C. Prescribe a course of topical corticosteroid cream.
D. Refer immediately for Mohs micrographic surgery.
E. Arrange for cryotherapy in the clinic.
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Ultrasonographic picture taken from a patient with left ureteral stone with hydronephrosis, created in Taiwan
Image by morning2k CC BY 2.5 · Source

A 45-year-old male presents to the emergency department with sudden onset severe left flank pain radiating to the groin. He reports some nausea but no vomiting. His temperature is 37.5°C, pulse 88 bpm, BP 130/80 mmHg, respiratory rate 16/min, oxygen saturation 98% on room air. On examination, he has significant left costovertebral angle tenderness. Urinalysis shows microscopic haematuria and trace leukocytes. His creatinine is 90 µmol/L (baseline unknown). An ultrasound of the kidneys is performed, shown in the image. Considering the patient's presentation and the findings demonstrated in the provided image, the most likely primary mechanism responsible for the severe pain experienced by this patient is:

A. Ischaemic injury to the renal tubules resulting from compromised blood flow.
B. Increased hydrostatic pressure leading to distension of the renal pelvis and collecting system.
C. Reflex spasm of the psoas muscle due to ureteral irritation.
D. Direct irritation of sensory nerve endings in the ureteral wall by the obstructing object.
E. Inflammatory response within the renal parenchyma secondary to bacterial invasion.
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A 55-year-old man presents to the emergency department with sudden onset severe abdominal pain radiating to the back. He has a history of hypertension and is a smoker. On examination, he is diaphoretic and in distress, with a blood pressure of 90/60 mmHg and a heart rate of 110 bpm. Abdominal examination reveals a pulsatile mass in the midline. What is the most likely diagnosis?

A. Acute myocardial infarction
B. Acute pancreatitis
C. Perforated peptic ulcer
D. Renal colic
E. Ruptured abdominal aortic aneurysm
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 55-year-old male presents with bilateral breast tenderness and swelling. He denies nipple discharge or systemic symptoms. His vitals are normal, and he takes no medications. Considering the clinical presentation and the findings depicted, which hormonal imbalance is most commonly implicated in the development of this condition in a male of this age group?

A. Excessive secretion of cortisol
B. Elevated serum prolactin
C. Increased oestrogen to testosterone ratio
D. Isolated deficiency of luteinising hormone
E. Primary hyperthyroidism
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 55-year-old male presents to the emergency department with a 2-day history of left lower quadrant abdominal pain, associated with fever (38.2°C) and mild nausea. He denies vomiting, diarrhoea, or rectal bleeding. On examination, he has localised tenderness in the left iliac fossa. His blood pressure is 130/80 mmHg, heart rate 85 bpm, respiratory rate 16 bpm. Blood tests show a white cell count of 14 x 10^9/L and CRP 80 mg/L. A CT scan of the abdomen and pelvis is performed (image provided). Considering the patient's presentation and the findings on the provided image, which of the following is the most appropriate initial management strategy?

A. Intravenous antibiotics and hospital admission
B. Urgent surgical consultation for sigmoid colectomy
C. Oral antibiotics and outpatient management
D. Repeat CT scan in 24 hours to assess for progression
E. Immediate colonoscopy to assess the extent of disease
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Figure 3 of paper: Alveolar echinococcosis in a patient with immunosuppression.

(a) Abdominal gray-scale US shows an abscess-like hepatic image.
(b) Axial unenhanced CT shows a typical aspect of pyogenic liver abscess.
Image by Wenya Liu, Éric Delabrousse, Oleg Blagosklonov, Jing Wang, Hongchun Zeng, Yi Jiang, Jian Wang, Yongde Qin, Dominique Angèle Vuitton, Hao Wen CC BY 4.0 · Source

A 58-year-old male, on chronic immunosuppressants, presents with vague abdominal pain. The images are shown. What is the MOST likely causative organism?

A. Klebsiella pneumoniae
B. Echinococcus multilocularis
C. Escherichia coli
D. Staphylococcus aureus
E. Entamoeba histolytica
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A 55-year-old man with a history of hypertension presents for a routine check-up. His blood pressure is consistently measured at 160/95 mmHg despite lifestyle modifications. He is currently on perindopril 5 mg daily. According to Australian guidelines, what is the most appropriate next step in managing his hypertension?

A. Switch to losartan
B. Refer for renal artery imaging
C. Add hydrochlorothiazide
D. Add amlodipine
E. Increase perindopril to 10 mg daily
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old man presents with increasing postprandial fullness and epigastric discomfort. A CT scan of the abdomen is performed. Based on the image, what is the MOST appropriate next step in management?

A. Initiate a trial of high-dose proton pump inhibitors
B. Esophageal manometry to assess esophageal motility
C. Surgical consultation for consideration of fundoplication
D. Reassurance and dietary modification
E. Barium swallow study to evaluate for esophageal strictures
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A 45-year-old man presents to his general practitioner with a 3-month history of persistent cough and occasional wheezing. He is a non-smoker and works as a carpenter. He reports that his symptoms worsen at work and improve on weekends. He has no significant past medical history and is not on any medications. What is the most likely diagnosis?

A. Viral upper respiratory tract infection
B. Pulmonary fibrosis
C. Chronic obstructive pulmonary disease (COPD)
D. Gastroesophageal reflux disease (GERD)
E. Occupational asthma
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Giant hiatal hernia, CT image. 63 year old man.
Image by Jmarchn CC BY 4.0 · Source

A 63-year-old man presents to his GP with a 6-month history of intermittent postprandial fullness and mild dysphagia, particularly with solid foods. He reports occasional regurgitation but denies significant heartburn or chest pain. His vital signs are stable, and physical examination is unremarkable. Recent blood tests show mild iron deficiency anaemia. The provided image is from a CT scan of the chest and upper abdomen performed as part of his investigation. Considering the clinical presentation and the significant anatomical finding demonstrated in the image, what is the most appropriate next step in the management of this patient?

A. Urgent upper gastrointestinal endoscopy to assess for malignancy.
B. Initiation of high-dose proton pump inhibitor therapy.
C. Prescription of iron supplements and dietary advice.
D. Barium swallow study to further characterise the anatomy.
E. Referral for surgical assessment and consideration of operative repair.
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A middle-aged man with a 20% estimated cardiovascular risk is already on lifestyle modifications and statin therapy. Which of the following investigations can help further assess or reclassify his cardiovascular risk?

A. Coronary artery angiogram
B. Echocardiogram
C. Stress echocardiogram
D. Coronary artery calcium score
E. Exercise ECG
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